Wednesday, January 29, 2020

Therapeutic Cloning to Obtain Embryonic Stem Essay Example for Free

Therapeutic Cloning to Obtain Embryonic Stem Essay Therapeutic Cloning to Obtain Embryonic Stem Cells Is Immoral The point is to cause each of us to think deeply about whether there is any essential difference between the reality of [World War II] Nazi experiments and therapeutic cloning. In this two-part viewpoint, David A. Prentice and William Saunders discuss the science and the ethics of therapeutic cloning. In the first part, Prentice argues that creating clones for the purpose of embryonic stem cell research, called therapeutic cloning, is no different from reproductive cloning, which creates a living human child. Also, he points out, therapeutic cloning is not therapeutic for the embryo. In the second part of the viewpoint, Saunders builds on Prentices argument and goes even further. He argues that therapeutic cloning is really no different than the horrific experiments performed by the Nazis during World War II. Saunders notes that supporters of embryonic stem cell research contend that the research is beneficial to humankind; however, Saunders argues, the Nazis used this same reasoning to Justify research on the mentally ill, the disabled, and the feeble-minded. Prentice and Saunders are senior fellows at the Family Research Council, a onservative Christian think tank and lobbying organization. As you read, consider the following questions: 1. Why does Prentice claim that therapeutic cloning will lead to reproductive cloning? 2. What was the point of the Nuremberg Code, according to Saunders? 3. Why does Saunders say that therapeutic cloning violates the Nuremberg Code? Part I Cloning always starts with an embryo. The most common technique proposed for human cloning is called somatic cell nuclear transfer (SCNT). This cloning is accomplished by transferring the nucleus from a human somatic (body) cell into an egg cell which has had its chromosomes removed or inactivated. SCNT produces a human embryo who is virtually genetically identical to an existing or previously existing human being. Proponents of human cloning hold out two hopes for its use: (1) the creation of children for infertile couples (so-called reproductive cloning), and (2) the development of medical miracles to cure diseases by harvesting embryonic stem cells from the cloned embryos of patients (euphemistically termed therapeutic cloning). All Human Cloning Produces a Human Being All human cloning is reproductive. It creates†reproduces†a new, developing human intended to be virtually identical to the cloned subject. Both reproductive cloning and therapeutic cloning use exactly the same technique to create the clone, and the cloned embryos are indistinguishable. The process, as well as the product, is identical. The clone is created as a new, single-cell embryo and grown in the laboratory for a few days. Then it is either implanted in the womb of a surrogate mother (reproductive cloning) or destroyed to harvest its embryonic stem cells for experiments (therapeutic cloning). It is the same embryo, used for different purposes. In fact, the cloned embryo at that stage of development cannot be egg and sperm. Trying to call a cloned embryo something other than an embryo is not accurate or scientific. Biologically and genetically speaking, what is created is a human being; its species is Homo sapiens. It is neither fish nor fowl, neither monkey nor cow†it is human. Created in Order to Be Destroyed Therapeutic cloning is obviously not therapeutic for the embryo. The new human is specifically created in order to be destroyed as a source of tissue C, as Robert P. Lanza and colleagues report in a 2000 JAMA article]: [Therapeutic cloning] requires the deliberate creation and disaggregation ofa human embryo. Most cloned embryos do not even survive one week, to the blastocyst stage, when they are destroyed in the process of harvesting their cells. Experiments with lab animals show that even these early embryos have abnormalities in genetic expression. Beyond the abnormalities caused by the cloning procedure, embryonic stem cells from cloned embryos will still face problems for their use, including the tendency to form tumors, and significant difficulties in getting the cells to form the correct tissue and function normally. Therapeutic Cloning Leads to Reproductive Cloning Because there is no difference in the nuclear transfer technique or the cloned embryo, allowing therapeutic cloning experimentation to proceed will inevitably lead to reproductive cloning. The technique can be practiced and huge numbers of cloned embryos produced. In fact, the lead scientist of the South Korean team that first cloned human embryos in February 2004 in a press conference on their experiments that the cloning technique developed in their laboratory cannot be separated from reproductive cloning. His statement affirms what others have pointed out before: allowing therapeutic cloning simply prepares the way for eproductive cloning. Human cloning is unsafe and unnecessary. There are no valid or compelling grounds†scientific or medical†to proceed. A comprehensive ban on human cloning is the only sufficient answer. Part II As Dr. Prentice has shown, cloning indisputably destroys innocent human life. This basic truth should lead the world to reject human cloning. However, in an effort to extricate human cloning from this ethical vise grip, its supporters attempt to draw a distinction between human life, which begins at conception, and human personhood, which begins only at their say-so. Unfortunately, the arbitrary denial f personhood to human beings has a long and cruel history. The Nuremberg Code, formulated in the years after World War II, is particularly instructive with regard to the current debate on human cloning. For instance, when the principal author of the report on human cloning issued by the National Academy of Sciences testified before the Presidents Council on Bioethics, he stated that reproductive cloning would violate the Nuremberg Code: The Nuremberg Code, with which I am in full agreement, outlines those kinds of things you would not simply [do] for the sake of knowledge that involve human subjects. The Nuremberg Code The Nuremberg Code is a body of ethical norms enunciated by the Nuremberg Tribunal, which, after World War II, had the responsibility of Judging the actions of the Nazis and their allies. The point of the code was to restate and apply the established ethical norms of the civilized world. Nazis Deemed Some Life Unworthy Nazi laws had defined Jews and other undesirables as non-persons. Eventually, camps and killed. However, before the killing in the camps began, the Nazis had engaged in an extensive campaign of euthanasia against the mentally and physically handicapped, which not only foreshadowed but also prepared the way for the xtermination camps. In his book The Nazi Doctors, Robert Jay Lifton draws our attention to a book titled The Permission to Destroy Life Unworthy of Life, written during the campaign. Lifton writes: [It was] published in 1920 and written Jointly by two German professors: the Jurist Karl Binding and Alfred Hoche, professor of psychiatry at the University of Freiburg. Carefully argued in the numbered-paragraph form of the traditional philosophical treatise, the book included as unworthy life not only the incurably ill but large segments of the mentally ill, the feeble-minded, and retarded and deformed children. T]he authors professionalized and medicalized the entire concept; destroying life unworthy of life was purely a healing treatment and a healing work. The Nazis were determined to cleanse the genetic pool to produce better Aryans. Nazi officials announced that under the direction of specialists all therapeutic possibilities will be administered according to the latest scientific knowledge. The result of this therapeutic treatment of inferior lives was that eventually a network of some thirty killing areas within existing institutions was set up throughout Germany and in Austria and Poland. In their book, The Nazi Doctors and the Nuremberg Code, George Annas and Michael Grodin reveal that: At the same time that forced sterilization and abortion were instituted for individuals of inferior genetic stock, sterilization and abortion for healthy German women were declared illegal and punishable (in some cases by death) as a crime against the German body. As one might imagine, Jews and others deemed racially suspect were exempted from these restrictions. On November 10, 1938, a Luneberg court legalized abortion for Jews. A decree of June 23, 1943, allowed for abortions for Polish workers, ut only if they were not Judged racially valuable. Later, the Nazis created the extermination camps for the Jews and other inferior races. In the camps, Nazi doctors engaged in cruel experiments on the Jews, Gypsies, Poles, and others. They exposed them to extreme cold to determine the temperature at which death would occur. They injected them with poisons to see how quickly certain lethal elements moved through the circulatory system. They subjected twins to all manner of disabling and brutal experiments to determine how genetically identical persons reacted to different conditions. Some of the experiments were nonetheless designed to preserve life†not of the subject, but of, for example, German pilots who were forced to parachute into freezing ocean waters. Everyone agrees the Nuremberg Code prohibits reproductive cloning. What relevance does it have for therapeutic cloning? If human embryos are human beings, then therapeutic cloning, which creates an embryo only to destroy it in the process of exploiting its stem cells, violates a cardinal principle of the Nuremberg Code: There is to be no experimentation on a human subject when it is known that death or disabling injury will result. Regardless of the good that might be produced by such experiments, the experiments are of their very nature an immoral use of human beings. Subverting the Meaning of Healing Recall how the Nazis subverted the meaning of heali ng. Recall how they used the them. Recall that the Nazis eliminated those unworthy of life in order to improve the genetic stock of Germany. Recall how the Nazis undertook lethal experiments on concentration camp inmates in order, in some cases, to find ways to preserve the lives of others. The point is not to suggest that those who support therapeutic cloning are, in any sense, Nazis. Rather, the point is to cause each of us to think deeply about whether there is any essential difference between the reality of those Nazi experiments and therapeutic cloning. As we have shown, each case involves a living human being, and that human being is killed in the aim of a perceived higher good. Cloning proponents try to distinguish between the two cases by saying that the cloned human being has no potential. But in each case, it is the actions of other human beings that rob the first of potential (in the first case, the actions of Nazi executioners; in the second, the laboratory technicians). In either case, the human ubject is full of potential simply by being a living human being. Of course, almost miraculously, many of the inmates of the camps did survive when the allies rescued them. Equally miraculously, frozen embryos have been implanted in a womans womb and brought to live (and healthy) birth. As we have shown, every embryo is not merely potentially a life, but [is an] actual life, a human being from the first moment of existence. Furthermore, any living human embryo has the inherent potential to develop into a healthy baby. It is disingenuous for supporters of cloning to claim the cloned human embryo is only potential life because they plan o mandate by law that it be destroyed before it can come to birth. Regardless of its location, the human embryo, by its nature, is full of potential, unless the actions of adult human beings deprive it of the opportunity to realize that potential. Guard Against Inhuman Acts [Russian author] Alexander Solzhenitsyn, a man who chronicled and suffered under another ideology that denied the dignity of each and every human being, observed, Gradually it was disclosed to me that the line separating good and evil passes not through states, nor between classes, nor between political parties either, but right hough every human heart, and through all human hearts. This line shifts. Inside us, it oscillates. Solzhenitsyn did not regard the perpetrators of brutal crimes in his own country as inhuman monsters. Rather, he saw the essential truth†they were human beings, engaged in immoral acts. They engaged in those acts by dehumanizing the persons on whom their brutality was inflicted, and they did so in the name of (perhaps in the passionate belief in) a greater good. But Solzhenitsyn reminds us that, unless we are willing to admit that, for the best as well as for the orst of motives, we are also capable of inhuman acts, we will have no guard against committing them. No one is safe from brutality so long as we think that it is only inhuman others who are capable of inhuman acts. Rather, we will be secure when we are willing to look honestly at the objective reality of our acts, while realizing that we, too, are capable of acts that violate the inherent dignity of another, and refuse to engage in such acts despite the good we believe would result from doing otherwise. In the debate over the cloning and destruction of embryonic human beings, this essential truth must be our guide. Books Brian Alexander Rapture: How Biotech Became the New Religion.

Tuesday, January 21, 2020

Essay --

Plum Island is a fictional novel about a convalescing New York Police homicide detective named John Corey, who gets involved in a multiple murder investigation while he is supposed to be recovering from serious wounds. John is originally working as a consultant for the small township, where an old friend of his is the Chief of Police, but when he is relieved of this position, he continues the investigation on his own. Eventually the county detective assigned to solve the case, Beth Penrose, invites him to collaborate with her and the team solves the original double murder, and all of the murders committed by the same man, Frederic Tobin. John Corey is relaxing on his Uncle Harry's deck when Sylvester Maxwell, Chief of the local police, asks John to accompany him to the murder scene. Tom and Judy Gordon, biologists at the nearby Plum Island biological animal research center, and recent friends of John, have both been shot in the head on the deck of their home. John meets Detective Beth Penrose of the Suffolk County Sheriff's Office, Foster of the FBI, and a man named Ted Nash who says he is from the Department of Agriculture but turns out to be a CIA agent. The initial investigation focuses on the Gordons stealing a virus from the Plum Island facility and selling it to a foreign government. To this end, the team of Nash, Foster, John, Beth and Max are taken on a lengthy tour of the facility, including the uninhabited part of the island that contains a revolutionary war era abandoned fort. While on the tour, John and the team meet the head of security, Paul Stevens. They also learn that the Gordons were involved in researching a vaccine for Ebola, were amateur archeologists, and had free reign to bring their boat to and from work ... ... John and Beth take Tobin's boat to the ferry dock and Max meets them there. John heads for Manhattan to face the wrath of his NYPD supervisor. At his home, he finds a letter from the Gordons, written before their murder, verifying everything he has now discovered. John goes to meet with his supervisors and negotiate a way out of the trouble he is in for disobeying orders. The last chapter shows John teaching homicide investigation, as a retired police officer. It is several months after the Plum Island incident, and he misses the police force, but accepts what needed to happen. He is also unattached. John is surprised to se that Beth Penrose has enrolled in his class. She catches him up on the latest from Suffolk County, and is gently offering to be in his life again. While he initially resists, he announces to the class that he is taking her for drinks that night.

Monday, January 13, 2020

Mentor

Instead of cursing the dark we have to light a candle; instead of looking down at the gutter at the roadside on a moonless night why not look up and appreciate the stars   in the sky? We should put passion in every undertaking. And instead saying â€Å" It’s cloudy outside but it’s a Sunday,† why not make it as an opportunity and say   â€Å"It’s a   great Sunday!† Meaning you’re optimistic that the day   would turn out right  Ã‚   because you are free from your office work—of your responsibility here–  Ã‚   despite the clouds hovering at the horizon. Right? In short we, all of you (managers, supervisors, section heads) should try to inspire others through your thoughts, words and deeds. First you should think and act as mentors and not mere managers or slave drivers of employees.   A mentor says â€Å"we have to do this way,† rather than ordering a subordinate â€Å"to do that way.† Make yourself  Ã‚   part of the solution – a member of the team. As a mentor you take every problem as a new challenge. As proactive mentor you have to be ahead of the situation or you have to put up measures to prevent potential problems   to crop up. To be an effective mentor you have to have the unlimited capacity to understand. How? Review your college psychology, about human nature or behavior, about motivation and aspirations of individuals. Make your subordinates feel that their aspirations and ambitions would be addressed by playing   their roles in the company. Make their individual ambitions and the company’s objective   one. Make them proud to belong to the company since they are being taken care of including their loved ones. To be a competent mentor every manager should have an open line of communication. You have to remove the partitions and cubicles. Let every worker approach you any time of the day – or night — and help him solve even his personal problem. As a mentor your responsibility does not end after office hours. The communications line should be open 24 hours a day. Mentoring is like coaching a football or basketball team. A coach is a mentor-leader —not a manager– because he inspires people. Your effectiveness as a coach could be measured on how the athletes play the game and not on the number of games won. The objective of the manager is to win all the games. As for the coach? His foremost consideration is the welfare of the individual players including their future and direction. Winning is secondary. Winning is not the objective. Winning a game or the championship should be the result of mentoring. No amount of shouting, cursing or suspension could make a player give a 100-percent contribution to a game if he is not inspired to play. He only gives his best because of the motivations from his coach. An example is Carter of the popular movie Coach Carter. He made men out of the spoiled and undisciplined youngsters. He transformed their lives—and their future. He considered every game lost an opportunity for each of his players to improve and do better. Carter   provided them reasons to live a beautiful and fruitful life. Another organization where you can find a mentor-leader is the Army. It is not the platoon leader but it’s usually the platoon sergeant who motivates the infantrymen during battles. One factor that inspires the soldiers could be the courage of the sergeant. And he leads in front of his platoon every skirmish. Because he has the extensive knowledge and experiences acquired from previous battles his men have confidence of his leadership. They know that what the sergeant is doing is  Ã‚   for their welfare and to reduce casualties.   In short extensive knowledge and courage play an important role in motivating people. And you can have more knowledge by attending managerial and motivational workshops on your initiative and on your own time. In short self-improvement. Another role you should play as leader is that of a facilitator. You should group your subordinates into teams not as work-related groups, like budget, accounting,   or disbursing section .Each team has an objective to accomplish—just like every squad in the army. Each team member has a defined role to play or a specialization.The men in a squad don’t carry the same type of weapon. One carries a bar or a special weapon which is effective for long range shooting. Another carries a machine gun for close combat. Others carry assault   rifles for the final push. Others carry sniper’s rifle with night vision for evening assault, and so forth. And in the absence of the point -man, the next in rank can take over to accomplish the objective of the team since every member’s role is clearly defined. So you have a logistical team rather than a dispatching section. Each team leader is empowered to make decisions. In case of misunderstanding or conflict in the implementation of an office policy, as manager or supervisor you act as collaborator but not as compromiser. As team member you consider everyone in the group as your   colleague or peer not as your immediate supervisor or your direct subordinate. Each role should be defined not by the ranking of the position but by specialization or skills. Thus, the secretary   becomes communications specialist and the telephone operator the   solutions provider—   for she gives answers to queries, Right? With these changes each can assert his role in the organization and he could measure his overall contribution. Even the janitor must have a position fitted to his contribution — as sanitation specialist. Try to imagine a single day without a janitor. You will find that the following day everything is in chaos or the office smelly. In case of conflict, as facilitator you initiate collaborative work, you initiave   comprehensive cooperation from all the members of the team. For an example in the advertising department, you yave to facilitate the production of the best creative idea for a promotional campaign. In this case you don’t have to criticize ideas presented. You have to facilitate the frution of the ideas into a useful concept. As facilitator you have to be highly assertive so it would be faster for a collegial decision to crop up from the team. Another role you should play as supervisor is that of a monitor. In short you have to record and take note of the progress of each team in your group. You don’t have to record their attendance nor whether they come on time or leave the office earlier. That’s not the point. As monitor you record as to how far they are from the goal. You have to be goal-oriented. You manage by objective. To be an effective monitor you have to be competent about   information management—the ins and outs of the system.In short you have your own system to grade your members. In the military there is such thing as demerits. For example you wear a complete uniform you would be given 100 merits. Any stain or dirt in the uniform, or improper wearing of a single insignia   the officer would give you the corresponding demerits. In this way your team members know their goal if they could make   you objective and make it   perfectly.. The military for example, has its own counterintelligence group. This way the military plays it safe by moving ahead of its enemies. This means you monitor the contribution of each member of the team and advice them from time to time as the necessary adjustments needed in their activities. Another function you should do as manager is that of a coordinator. In this situation you act not only as the coach of the team. You act at   the same time  Ã‚   the team captain or   the playing coach. You coordinate the maneuvers on the court as team captain. All the members of the team observe you from a distance as to what signals you are transmitting to them. As coordinator you know the specialized skill of each member. Like basketball, you know   how the guard or the forwards functions during set plays. You know the capacity   of your center or you know who would be the slotman or pointmaker during crucial time of the game. In short each man has a specialization—just like in your department or section. In basketball, the team captain sometimes decide  Ã‚   as to when they   need   to rest – and not necessarily the coach–   and transmit this need to the coach or the bench officials for the team to take a rest or take a time out to   change plan of  Ã‚   maneuvers . Compared to our company, as facilitator you must have the hands-on knowledge of the operation of your division or section.You cannot play as team captain if you don’t know the limit of your teammates, right? To summarize the following table show you the roles and the competencies needed: ROLES   COMPETENCIES NEEDED MENTOR       Big understanding; open-mindedness, effective verbal and oral Communications; ;extensive understanding of human Motivations; example that of a coach; can   emphatize FACILITATOR  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   team-building skills; delegation of authority; assume Responsibility; will not compromise solution; example That of a college instructor;example:   basketball team captain MONITOR     Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Proactive and goal-orientation; ability to detect Weaknesses; extensive analytical ability; example: a high school teacher; another example is the Army’s demerit system. COORDINATOR  Ã‚  Ã‚  Ã‚  Ã‚   Proactive; ability to measure capacity and limits; ex: team captain;   he gets the opinion of the members of the team to arrive at a good decision; ability to get the attention of every member of the team; ability to get respect from the team. Case 1 Shaheen Matombo, staff member The case of Shaheen is not an isolated one. It is always the problem of single mother who doubles as head of the family. Shaheen is not a hopeless case. In fact Shaheen has offered an alternative schedule of 8:30 a.m. in exchange for a 30-minute lunch break. As CEO I would suggest to Andre Tate, Shaheen’s manager, to adopt the staff member’s offer of arriving at 8:30 with 30-minute lunch break, with off at 5 p.m., just like everybody in the office. As manager   it is the foremost to maintain manpower, especially that   Shaheen is a product of a computer college. It is the goal of Shaheen’s immediate supervisor to give the newcomer—three months at work—a chance to develop herself in her workplace. In this age of computers,   and flexible time, the offer of Shaheen is laudable.   Morale of her co-workers would not be affected if the change of Shaheen’s schedule would be known by everybody in the office.And   the same flexible time schedule would be offered to anybody who have the same reasons that of Shaheen. As manager, Andre should also provide a counteroffer. Meaning, Shaheen would follow her suggested schedule religiously.And a single late or failure to follow the schedule may mean she has to revert to the 8 a.m. regular time. During contingency, Shaneen would be given the chance to work online at home, so by the time she will be at the office she would not miss any important call. A system would be installed that calls made at 8 a.m. to the office would be coursed through the home telephone or computer of Shaheen at home. Another counteroffer would be for Shaheen to observe her suggested schedule but without coffee breaks of 15 minutes in the morning and another coffee break of 15 minutes in the afternoon. In short let Shaheen eat at his work station in exchange for her coming at 8:30 p.m. Since Shaheen is a computer graduate, sooner she would learn the ropes and could be effective in her work. As manager, Andre’s work is to maintain cohesion, morale and develop through training all the employees, not only Shaheen. As manager, Andre’s responsibility is to develop human resources in the company, particularly at this time when it would be hard to hire competent employees who are readily knowledgeable with office work. One of the   four approaches to effective values (HM 2022, frame 17 of lecture 2) is emphasis on human relations where the goal of the manager is maintaining human relations. Shaheen stay in the office can be considered probationary for it   takes   from three to six months before an employee becomes regular. Assuming Shaheen is already a regular staffer, the more that she should be retained and given the chance to improve herself.   In this case, Andre may assign a veteran worker or her supervisor as her office mentor. Shaneen needs the guidance of a facilitator and coordinator who understands her first and second willing to help her until she may be six months in office. In this way, if she would not improve, Andre have the reason to look for her replacement or put her in a job that does not require her to be at 8 a.m.. Of she may be given flexible time schedule to suit her work at home. The manager should understand the situation of Shaneen from the poiont of view of a parent. The manager should try to wear the shoes of Shaheen to undertanding extensively the situation Shaheen is in. As mentor, Andre should inspire Shaheen to work better and improve in her work. Andre should have the capacity and the patience to work with a worker like Shaneen For sooner, Shaheen may improve for she has the potential to be an effective worker.               

Sunday, January 5, 2020

Personal Narrative I Am Balder - 911 Words

I am Balder. I live in Norrvegr. I am a Norseman. I am the eldest of four children. I dress in typical Scandinavian clothing, I typically wear linen or wool shirt and trousers, spun and woven by my mother and sisters in our home. The women wear dress like garment called shift made of same material. Over that they wear a dress open at the sides held with shoulder straps. In colder weather they wear cloaks or shawls. Clothing is held in place by brooches. Our shoes and boots are made of calfskin or goatskin. And of course animal skins to keep warm. My parents’ marriage, like most marriages, was prearranged by their families. We live in a modest house built of wood and stone. It has three rooms with walls made of wooden sticks covered with mud keep the wind and rain out. Our floor is dug below ground level, and our roof is made of sod. We have a hearth to provide warmth and serve as a place to cook. When sitting my father used a chair called the â€Å"high seat† while the rest of the family sat on benches. We slept on raise platforms on either side of a hearth. My daily life consists mostly of farming, although the growing season is very short here in Scandinavia. I mostly grow a variety of fruits and vegetables: onions, beats, and cabbage. Also barley, wheat and oats, which we use for making flour, porridge and ale. I also raise livestock which sometimes consists of goats, sheep, cattle, geese, chickens and pigs. We ate mostly what we could produce our farm, but also had the